Metal-coordinated imprinted polymers

Surface modified metal-coordinating imprinted polymers... 

Molecularly imprinted polymers (MIPs) may be prepared according to a number of approaches that are different in the way the template is linked to the functional monomer and subsequently to the polymeric binding sites (Table 5.1) (see Chapter 4). Thus, the template can be linked and subsequently recognised by virtually any combination of cleavable covalent bonds, metal ion coordination or non-covalent bonds. The first example of molecular imprinting of organic network polymers introduced by Wulff (see Chapter 4) was based on a covalent attachment strategy, i.e. covalent monomer-template, covalent polymer template [1]... 

DESIGN OF MOLECULARLY IMPRINTED POLYMERS BASED ON METAL-COORDINATION INTERACTION... 

Fig. 6.1. Preparation of molecular imprinted metal-coordinating polymers for Z>w-imidazole substrates.

Maximum binding capacities of these polymers towards different substrates and their apparent binding constant values were determined. These results indicate that the substrate selectivity exhibited by these imprinted polymers may involve a combination of cooperative two-site coordination of the Z> -imidazoles to the metal centres, as well as steric interaction with the cavity containing the binding sites. 

Fig. 6.2. Synthetic strategy for the preparation of surface imprinted metal-coordinating polymers using poly(TRIM) particles.

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