Metal complexes of amino

The VCD of amino acids and transition metal complexes of amino acids has been the subject of ongoing investigation in our laboratory (82-90), from which has emeiged new information on solution geometries and on the ring current mechanism for generating intense monosignate VCD intensity. 

Freeman, H. C. (1973). Metal complexes of amino acids and peptides. In Inorganic Biochemistry (G. L. Eichhorn, ed.), pp. 121-166. Elsevier, Amsterdam. 

Kinetics and stereochemistry of deuterium exchange of the a-hydrogen of an amino acid moiety in metal complexes of amino acid Schiff bases with or/Jio-hydroxy-acetophenone have been studied by Belokon et al.249). 

R. W. Hay and D. R. Williams, Metal Complexes of Amino-acids, Peptides and Proteins , in each odd issue of... 

Stereoselectivity in the metal complexes of amino acids and dipeptides has been reviewed by Pettit and Hefford,87 and will not be discussed further here. 

To examine the effects of coordination and hydrogen bonding, Nakamoto el al. made extensive IR measurements of the COO stretching frequencies of various metal complexes of amino acids in D2O solution, in the hydrated crystalline state, and in the anhydrous crystalline state. The results showed that, in any one physical state, the same frequency order is found for a series of metals, regardless of the nature of the ligand. The antisymmetric frequencies increase, the symmetric frequencies decrease, and Ihe separation between the two frequencies increases in the following order of metals ... 

The detailed structural study of metalloproteins was preceded by the study of small molecule metal complexes of amino adds and peptides [478]. The development of force fields for modeling metalloproteins might, logically, also begin with molecular mechanics modeling of amino acid and peptide complexes that have metal-ligand interactions of the type seen in the metalloprotein of interest. In this way, force-field... 

Stereoselectivity in the Metal Complexes of Amino Acids and Dipeptides... 

Scheme 1.23 Trimerization of metal complexes of amino acids.

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