Metal-based receptors

Beer PD, Bayly SR (2005) Anion Sensing by Metal-Based Receptors. 255 125-162 Bertini L, Bruschi M, de Gioia L, Fantucci P, Greco C, Zampella G (2007) Quantum Chemical Investigations of Reaction Paths of Metalloenzymes and Biomimetic Models - The Hydrogenase Example. 268 1-46 Bier FF, see Heise C (2005) 261 1-25... 

Beer PD, Bayly SR (2005) Anion Sensing by Metal-Based Receptors. 255 125-162... 

Electrochemical and Optical Sensing of Anion Systems by Transition Metal Based Receptors, Coord. Chem. Rev. 205, 131—55. 

Metal-based receptors provide excellent frameworks for anion host organisation and can act as reporter groups in electrochemical and luminescent anions sensing applications. 

Many aspects of anion recognition by metal-based receptors have been covered in previous reviews [1-5]. This review is not intended to be comprehensive rather, it provides an overview of the subject with particular reference to the specific properties that metal-containing sub-units impart to this class of anion sensor. The most recent advances in the field are also detailed including the use of metallo-receptors in dendrimer, functionalised nanoparticle and surface-bound anion sensors. 

Preorganisation of redox anion sensors on electrode surfaces is a promising new technique for electrochemical anion sensing. Self-assembled monolayers or thin polymer films of metal-based receptors have the potential to generate an amplified response to anion binding akin to the dendritic effect. 

Metal-based receptors which are able to form preorganised monolayers on planar electrodes can be expected to do the same on the surface of nanoparticles, leading to a surface sensing amplification effect. The very large surface area of nanoparticles could also allow greater overall sensitivity to anions. 

Beer PD, Cadman J. Electrochemical and optical sensing of anions by transition metal based receptors. Coord Chem Rev 2000 205 131. 

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