Metabolism endocrine disruptors

Endocrine disruptors are chemical substances that interfere with, or have adverse effects on, the production, distribution, or function of these same hormones . These substances do not affect growth or cause increased mortality. They affect the development of organisms which is manifested in alterations of reproductive capacity or metabolic disorders of many steroid hormones. Some aquatic invertebrate species (cladocerans, mollusks) with a short reproduction time have been intensively studied as the... 

The health effect of endocrine disruptors is further complicated by the fact that an endocrine disrupter or a family of endocrine disruptors may have multiple mechanisms of actions. For example, PCBs may mimic estrogen, prevent binding of thyroid hormone to thyroid binding globulin, and accelerate the metabolism and excretion of several steroid hormones. 

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