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Metabolic pathway recipe

Optimization of a Multi-Product Microbial Cell Factory for Multiple Objectives - A Paradigm for Metabolic Pathway Recipe... [Pg.401]

Keywords Multi-product microbial cell factory. Mixed integer MOO (MIMOO), Metabolic pathway recipe, Pareto-optimal set. [Pg.401]

The optimization of the Pareto-optimal metabolic pathway recipe by genetic manipulations shows that the triple-enzyme manipulation has the best non-dominated flux ratios due to the flexibility in changing enzjrmatic reaction rates to enhance the desired flux ratios (Figs.l3.3A and 13.4A). The left and right Pareto-optimal segments of single-enzjmae... [Pg.415]

Table 13.2 Pareto-optimal metabolic pathway recipe for 2-enzyme knockouts represented by the three labelled chromosomes in Fig. 13.2. The flux ratios are listed in the second, third and fourth column (chromosomes Ai, Bi and B2, respectively) for each enzyme. The same enzymes (G6PDH and MetS3mth) are knocked out in both chromosomes Aj and B2. Table 13.2 Pareto-optimal metabolic pathway recipe for 2-enzyme knockouts represented by the three labelled chromosomes in Fig. 13.2. The flux ratios are listed in the second, third and fourth column (chromosomes Ai, Bi and B2, respectively) for each enzyme. The same enzymes (G6PDH and MetS3mth) are knocked out in both chromosomes Aj and B2.
See other pages where Metabolic pathway recipe is mentioned: [Pg.23]    [Pg.401]    [Pg.402]    [Pg.403]    [Pg.413]    [Pg.414]    [Pg.416]    [Pg.421]    [Pg.23]    [Pg.401]    [Pg.402]    [Pg.403]    [Pg.413]    [Pg.414]    [Pg.416]    [Pg.421]    [Pg.270]    [Pg.261]   
See also in sourсe #XX -- [ Pg.402 , Pg.403 , Pg.413 ]



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