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Messenger RNA stability

Regulation of Messenger RNA Stability Provides Another Control Mechanism... [Pg.394]

Ross, J. (1996) Control of messenger RNA stability in higher eukaryotes. Trends Genet., 12, 171-175. [Pg.11]

Grunberg-Manago M (1999) Messenger RNA stability and its role in control of gene expression in bacteria and phages. Annu Rev Genet 33 193-227... [Pg.127]

All eukaryotic cells have four major classes of RNA ri-bosomal RNA (rRNA), messenger RNA (mRNA), transfer RNA (tRNA), and small nuclear RNA (snRNA). The first three are involved in protein synthesis, and snRNA is involved in mRNA splicing. As shown in Table 37-1, these various classes of RNA are different in their diversity, stability, and abundance in cells. [Pg.341]

Messenger RNAs exist in the cytoplasm as ribonu-cleoprotein particles (RNPs). Some of these proteins protect the mRNA from digestion by nucleases, while others may under certain conditions promote nuclease attack. It is thought that mRNAs are stabihzed or destabilized by the interaction of proteins with these various structures or sequences. Certain effectors, such as hormones, may regulate mRNA stability by increasing or decreasing the amount of these proteins. [Pg.394]

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Messenger RNA

Messengers

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