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Mesenchyme factor stimulating differentiation

Another aspect to consider is the cell source, cellular response and cellular affinity for the scaffold. ACL fibroblasts were shown to respond to specific growth factors, dynamic mechanical stimulation and static tension, but are known to have a low doubling rate, and a suitable source of autologous ACL fibroblasts is not yet available. This is why other sources, such as mesenchymal stem cells from bone marrow, are under investigation and seem to be an excellent cell source. They have the potential to differentiate into cells of multiple mesenchymal lineages. ... [Pg.626]

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Differentiation Factors

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