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Meperidine chemical name

Meperidine hydrochloride (the full name) is a synthetic opioid. It is synthesized by the reaction of chemicals not found in opium. Specifically, meperidine hydrochloride is produced by the reaction of dichlorodi-ethyl methylamine with benzyl cyanide, to produce ethyl l-methyl-4-phenyl-isonipecotate hydrochloride (meperidine s chemical name). Some references to meperidine classify it as a totally synthetic opioid. Semi-synthetic opioids are produced by using one of the opiates as a starting material. Two examples of semi-synthetic opioids are hydrocodone and heroin. Hydrocodone is produced by the chemical modification of codeine, while heroin is made by chemically altering morphine. [Pg.309]

Meperidine hydrochloride is designated by the following chemical names ethyl 1-methyl-U-phenylisonipec-... [Pg.177]

During the late 1930s some 4-phenylpiperidine derivatives were examined as potential spasmolytics on the basis of their chemical relationship to atropine. The antinociceptive properties of one member, ethyl 1-methyl-4-phenyl-piperidine-4-carboxylate, was detected in screening tests and the compound was subsequently introduced into clinical use by Eisleb and Schaumann in 1939. The compound, well known as pethidine in Europe and meperidine in North America (proprietary names include Demerol, Dolantin, and Dolosal), was soon in widespread use for the relief of pain, and it is remarkable how pethidine, the original non-opioid-derived opioid analgesic, has retained its popularity for many years in the face of competition from other synthetic analgesics introduced since 1939. [Pg.161]


See other pages where Meperidine chemical name is mentioned: [Pg.104]    [Pg.468]    [Pg.213]   
See also in sourсe #XX -- [ Pg.94 ]




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Chemical name

Meperidine

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