Mendeleev-like nano-periodic tables

Recently, first steps toward the fulfillment of this expectation have been realized by publication of the first Mendeleev-like nano-periodic tables for predicting the self-assembly modes of soft nano-element modules. More specifically, the self-assembly properties of soft nano-elements such as amphiphilic dendrons (i.e., [S-1] nano-elements) were systematically investigated by Percec, Rosen and colleagues [151]. They reported a prediction accuracy for resulting self-assembled structures of 85-90% based on the a priori use of dendron CNDPs. These issues will be described later in Section 6.6.3. 

We now examine recent progress reported by Percec, Rosen and colleagues [151] that has clearly demmistrated the first working examples of predictive, Mendeleev-like nano-periodic tables. These Percec nano-periodic tables clearly demonstrate a priori predictions for the mode of [S-l]-type amphiphilic dendron self-assembly into supramolecular dendrimers with 85-90% accuracy. Quite remarkably, as proposed in the original concept [137], these self-assembly modes may be accurately predicted based on simply knowing the CNDPs (size, shape, surface chemistry, and flexibility) for the amphiphilic dendron primary structure, as will be described in the next sectimi. 

Fig. 32 The first examples of Mendeleev-like nano-periodic tables have recently fulfilled the predictions for expected nanoscale property patterns and trends [137, 138]. Percec and Rosen [151] have reported the first three nano-periodic tables for predicting the self-assembly patterns for [S-l]-type amphiphilic dendrons, with predictive accuracies of 85 to >90%, based on knowledge of the primary dendron CNDPs, namely, size, shape, surface/apex chemistry, and flexibility/ rigidity [94].

Like proteins, the primary structures of the amphiphilic dendrons determine their tertiary structure. As such, Percec has compared dozens of his AB2- and ABs-derived dendron libraries in an effort to determine trends or nano-periodic self-assembly patterns as proposed by others [137]. Percec s seminal comparison produced the first three Mendeleev-like, predictive nano-periodic tables for the self-assembly of aryl ether dendrons [151]. The first of these nano-periodic tables is shown in Fig. 36. 

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See also in sourсe #XX -- [ ]

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