Membrane proteins assembly

Van Heijne G. Membrane Protein Assembly, R. G. Landes, Austin, TX, 1997. 

Chen, M., Xie, K., Jiang, F., Yi, L. and Dalbey, R. E. (2002). YidC, a newly defined evolutionarily conserved protein, mediates membrane protein assembly in bacteria, Biol. Chem., 383, 1565-1572. 

Gafvelin, G., Sakaguchi, M., Andersson, H., and von Heijne G. (1997). Topological rules for membrane protein assembly in eukaryotic cells./. Biol. Chem. 272, 6119-6127. 

II. Overview of Membrane Protein Assembly Pathways in Prokaryotic... 

Finally, peroxisomes contain another unique machinery for protein import and membrane protein assembly. 

Chloroplasts in higher plants have three membranes the outer and inner envelope membranes and the thylakoid membrane. Very little is known about membrane protein assembly into the two envelope membranes (Soil and Tien, 1998). The thylakoid has been better studied and in fact appears to use mechanisms very similar to those found in E. coli for membrane protein insertion (Dalbey and Robinson, 1999). Thus, SRP, SecA, SecYEG, YidC, and Tat homologues are all present in the thylakoid membrane or in the stroma (the Tat system was first identified in thylakoids, in fact). In contrast to E. coli, however, there are thylakoid proteins that appear to insert spontaneously into the membrane, insofar as no requirement for any of the known translocation machineries has been detected (Mant et al, 2001). 

Luirink, J., Samuelsson, T., and de Gier, J. W. (2001). YidC/Oxalp/Alb3 evolutionarily conserved mediators of membrane protein assembly. FEBS Lett. 501, 1-5. 

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