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Melaminophenyl arsenicals

Melarsoprol, a trivalent organic melaminophenyl arsenic compound, kills intracerebral parasites of both T. brucei gambiense and T. brucei rhodesiense. Melarsoprol accumulates via an adenosine/adenine transporter in trypanosomes and is believed to inhibit glycolytic enzymes. Melarsoprol leads to a rapid lysis of trypanosomes. Melarsoprol is highly toxic to humans. [Pg.179]

See other pages where Melaminophenyl arsenicals is mentioned: [Pg.2]    [Pg.6]    [Pg.24]    [Pg.2]    [Pg.6]    [Pg.24]    [Pg.9]   
See also in sourсe #XX -- [ Pg.6 ]



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