Meerwein-Ponndorf-Verly reduction

The secondary alcohols are oxidized to ketones by refluxing with aluminium isopropoxide, A1[0CH(CH3)2]3 [or Al(0-iPr)3], or potassium t-butoxide, KOC(CH3)3 [or KO-t-Bu]. A ketone such as acetone used in the reaction as refluxing agent is reduced to alcohol, 2-propanol. The reaction is known as the Oppenauer oxidation. The reverse reaction known as the Meerwein-Ponndorf-Verly reduction is the reduction of ketones to alcohols in the presence of alcohol such as 2-propanol. Potassium fert-butoxide can be used for the oxidation of primary alcohols. Aluminium isopropoxide in acetone is particularly used for... 

Oppenauer oxidations.5 Oppenauer oxidations and Meerwein-Ponndorf-Ver-ley reductions are usually carried out in the presence of aluminum alkoxides in at least stoichiometric amounts. Kagan et al. report that both reactions can be carried... 

The cyclic reduction mechanism that we are referring to is known as the Meerwein-Ponndorf-Oppenauer-Verly method and it is shown in the following generalized form ... 

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See also in sourсe #XX -- [ ]

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