Medicines Disulfiram

Also, Fox, DIsulfIram-Alcohol Side Effects, Letter to the Editor, 204 J,A,M,A, 271 (1968) Cahill, Safety of DIsulfIram, Letter to the Editor, 287 New Engiand Journai of Medicine 935 (1972),... 

Koff, Papadimas, Honlg, Alcohol In Cough Medicines Hazard to DIsulfIram User , Letter to the Editor, 215 J.A.M.A. 1988 (1971),... 

Disulfiram is an aversive therapy that works by inhibiting acetaldehyde dehydrogenase. Interactions between disulfiram and alcohol can result in potentially severe reactions, such as myocardial infarction, congestive heart failure, respiratory depression and death. Patients taking disulfiram should be warned of the possible presence of alcohol in liquid medicines, tonics, foods and even in toiletries and mouthwashes. Patient adherence to disulfiram is poor and there is a lack of strong evidence for its effectiveness, thus it is not routinely recommended. 

Calcium carbimide has effects and uses similar to those of disulfiram, and has been used in the treatment of chronic alcoholism (1). Its alternative name, cyanamide, has also been used to designate carbimide, which is used in veterinary medicine. 

Assistant Clinical Professor, University of California, San Francisco School of Medicine Medical Director, California Poison Control System, Fresno Division Section II Disulfiram Selenium Paraquat and Diquat Section III Atropine and Glycopyrrolate Pralidoxime (2-PAM) Other Oximes... 

Koff RS, Papadim as I, Honig EG. Alcohol in cough medicines hazards to the disulfiram user. 

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