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Medical applications binding mechanism

The development of synthetic host compounds for the selective complexation of natural peptides is of considerable interest for possible medical applications as well as for biotechnology, where they could be used for the separation of oligopeptides from natural or industrial sources. In addition, the study of such supramolecular complexes can help to shed light on biologically important binding mechanisms... [Pg.185]

Medically, anions are of great importance in many disease pathways. Cystic fibrosis, a genetic illness affecting a significant proportion of society, is caused by misregulation of chloride channels (17). There is, therefore, a real need for selective halide detection, as established methods of chloride analysis are unsuitable for biological applications (18). Cancer is caused by the uncontrolled replication of polyanionic DNA. Anion-binding proteins have also been implicated in the mechanism of Alzheimer s disease (19). [Pg.3]


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See also in sourсe #XX -- [ Pg.26 ]




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Binding mechanisms

Medical applications

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