Meclomen - Meclofenamic acid

Stabler I, Kapui Z, Ambrus J L1994 Study on the mechanisms of action of sodium meclofenamic acid (meclomen) a double inhibitor" of the arachidonic acid cascade. Journal of Medicine 25 371-382 Stillman M, Schlesinger P 1990 Nonsteroidal antiinflammatory drugs nephrotoxicity. Archives of Internal Medicine 150 268-270... 

Two compounds of the fenamate class of antiinflammatory drugs are marketed in the United States. Mefenamic acid (Ponstel) is indicated only for analgesia and primary dysmenorrhea when therapy will not exceed 1 week. Meclofenamate sodium (Meclomen) is prescribed for rheumatoid arthritis and osteoarthritis. 

Mefenamic acid (Ponstel, Ponstan [United Kingdom], Dysman [United Kingdom]) and meclofenamate sodium [Meclomen] have been used mostly in the short-term treatment of pain in soft-tissue injuries, dysmenorrhea, and in rheumatoid and osteoarthritis. These drugs are not recommended for use in children or pregnant women. 

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