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Mechoulam

Mechoulam R (ed) (2005) Cannabinoids as therapeutics. Basel, Birkhauser Verlag, pp 1-272... [Pg.469]

Although it has been nearly 40 years since THC, the main active psychotropic constituent of the plant Cannabis sativa, was isolated (Gaoni and Mechoulam... [Pg.167]

Gaoni Y, Mechoulam R Isolation, structure, and partial synthesis of an active constituent of hashish. J Am Chem Soc 86 1646—1647, 1964 Gardner EL Addictive potential of cannabinoids the underlying neurobiology. Chem Phys Lipids 121 267-290, 2002... [Pg.177]

Mechoulam R The pharmacohistory of cannabis sativa, in Cannabinoids as Therapeutic Agents. Edited by Mechoulam R. Boca Raton, EL, CRC Press, 1986,... [Pg.179]

After identification of A9-THC as the major active compound in Cannabis and its structural elucidation by Mechoulam and Gaoni in 1964 [66], a lot of work was invested in chemical synthesis of this substance. Analogous to the biosynthesis of cannabinoids, the central step in most of the A9-THC syntheses routes is the reaction of a terpene with a resorcin derivate (e.g., olivetol). Many different compounds were employed as terpenoid compounds, for example citral [67], verbenol [68], or chrysanthenol [69]. The employment of optically pure precursors is inevitable to get the desired (-)-trans-A9-THC. [Pg.19]

Mechoulam R, Devane WA, Glaser R (1999) In Nahas GG, Sutin KM, Harvey DJ, Agurell S (eds) Marihuana and medicine. Humana, New Jersey, p 65... [Pg.38]

Taura F, Morimoto S, Shoyama Y (1996) J Biol Chem 271 17411 Morimoto S, Komatsu K, Taura F, Shoyama Y (1998) Phytochemistry 49 1525 Taura F, Morimoto S, Shoyama Y, Mechoulam R (1995) J Am Chem Soc 117 9766 Taura U (2004) Research report, Graduate School of Pharmceutical Sciences, Kyushu University. Available at http //www.nisr.or.jp/englishHP/report2004/NlSR04tam-a.pdf, last visited 29 June 2007... [Pg.39]

Mechoulam R, Lander N, University A, Zahalka J (1990) Tetrahedron Asymmetry... [Pg.39]

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See also in sourсe #XX -- [ Pg.24 , Pg.159 ]



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Mechoulam, Raphael

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