Mechanical sector transducers

Fig. 40. Two similar models for ATP synthase. (A) The Capaldi model shows cross-links between various Fq and F, subunits which result in blocking or not blocking enzymatic activity the open bow-ties are used to represent cross-links that do not affect the ATP synthase activity and the black bow-ties those that do. (B) The Junge model places emphasis on the structural sectors of the "motor" and the engine parts, the rotor and stator. See text for discussion. (A) Adapted from Ogilvie, Aggeler and Capaldi (1997) Cross-linking of the subunit to one of the three a subunits has no effect on functioning as expected if is a part of the stator that links the Fi and Fo ports of the Escherichia coliA TP synthase. J Biol Chem 272 16655 (B) Adapted from Junge, Lill and Engelbrecht (1997) A TP synthase an electrochemical transducer with rotatory mechanics. Trends in Biochem Sci 22 420. Also cf. model of Peter GrSber in color in Color Plate 17.

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