Mctal synthesis

The reactions of Type I and Type 111 2-butenyl-mctal reagents with chiral aldehydes have been reviewed from the perspective of this model W. R. Roush in Comprehensive Organic Synthesis, C. H. Heathcock, Ed., Vol. 2, p 1, Pergamon, Oxford 1990. 

Such J-mctals as Cu(I) [but not Cu(II)], form a variety of compounds with ethenes, for example [Cu(C2H4)(H20)2]C104 (from Cu, Cu2+, and C2H4) or Cu(C2H4)(bipy)+. It is necessary to mention that, of all the metals involved in biological systems, only copper reacts with ethylene [74b]. Such homoleptic alkene complexes can be useful intermediates for the synthesis of other complexes. The olefin complexes of the metals in high formal oxidation states are electron deficient and therefore inert toward electrophilic reagents. By contrast, the olefin complexes of the metals in low formal oxidation states are attacked by electrophiles such as protons at the electron-rich metal-carbon a-bonds [74c]. 

Morita, T., Okamoto, Y., and Sakurai, 11., Dealkylation reaction of acetals, phosphonate, and phosphate esters with chlorotrimethylsilanc/mctal halide reagent in acetonitrile, and its application to the synthesis of phosphonic acids and vinyl phosphates. Bull. Chem. Soc. Jpn., 54, 267, 1981. 

The first purposeful use of ATRA in polymer synthesis was in the production of telomers," In this early work, comparatively poor control over the polymerization was achieved and little attempt was made to explore the wider utility of the process. Some analogies may also be drawn with the work of Baraford et al. and others on transition mctal/organic halide redox initiation (Sections 3.3.5.1 and 7.6.2). ... 

In our previous paper the synthesis and characterization of conducting mctals containing poly[4-(tcrcphthaloylamino) salicylic add hydrazidc] (PIASH) were reported. 

Mctal-catalyzcd boiylaiion of alkanes and arenes for the synthesis of boronic esters (Ishiyama and Miyaura)... 

A. Polysaccharide Cleavage and Synthesis. B. Disaccharide, Hexoside and Glucuronide Metabolism. C. Mctal olism of Ilcxoses, Pentoses, and d-Carbon Compounds. D. Hexos-ainiia and Sialic. Acid Metabolism. E.. Aromatic Ring Synthesis. 

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