Maytenus chuchuhuasha

Maytenine, a pharmacologically active spermidine alkaloid from Maytenus chuchuhuasha (see Vol. 4 of these Reports), has been synthesized by two different routes.Details of the previously reviewed synthesis of ( )-tetrahydrolunari-dine (see Vol. 3 of these Reports) have been published. 

Maytenus spp. Chuchuara or chuchuhuasha from Peru contains an amorphous alkaloid which lowers body temperature and reduces blood pressure. (Raymond-Hamet and Colas, Bull. Acad. M d., 1935,114,139 Perrot, MUlat and Colas, Bull. Sci. Pharmacol., 1937, 44, 325.)... 

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