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Maybridge

CoX-2 Maybridge database (12.5 K) Catalyst search followed by GOLD docking 5 hits of 8 tested [113]... [Pg.101]

SIRT-2 Maybridge, Leadquest dbs, UNITY search 4 of 11 tested [122]... [Pg.101]

T-type calcium channel Maybridge (55 K) and ion channel inhibitor db (8 K), Catalyst search 3 hits of 25 tested [123]... [Pg.101]

MGL/FAAH Maybridge, Leadquest (a) UNITY, (b) GOLD No hits of 62 tested, 5 hits when retested inFAAH [210]... [Pg.110]

Maybridge pic, Trevillett, Tintagel, Cornwall PL34 OHW, UK. Website http //www.maybridge.com. [Pg.432]

Experimental Validation 11 Mining of the Maybridge database yielded two compounds that were synthesized and sent to NIH for the MBS anticonvulsant test. Very promising and exciting results have also been obtained. One of the compounds (C9) shows moderate anticonvulsant activity of ED50 between 30 and 100 mg kg (in mice), while the other (C8) is a very potent anticonvulsant agent with ED50 of 18 mg kg" in mice (ip). In summary, both compounds were found to be very active in both mice and rats (Table 16.2). [Pg.448]

Tab. 16.2 Results of anticonvulsant activity testing from anticonvulsant screening project at the National Institutes of Health (Maybridge database)... [Pg.451]

Maybridge, http //www.daylight.com/ products/databases/Maybridge.html, 2004. [Pg.455]

Maybridge Chemical Company Ltd., Cornwall, PL34 OHW England. URL www.maybridge.co.uk. [Pg.277]

Many commercial vendors and academic labs provide collection of compounds or fragments (Sigma-Aldrige, Available Chemicals Directory (ACD) (http //www.symyx.com), Maybridge (www.maybridge.com), TCI America (http //www. tciamerica.com), ChemDB (51) (http //cdb.ics.uci.edu), ZINC... [Pg.159]

Maybridge, Maybridge Chemical Company, Trevillet, Cornwall. [Pg.222]

Figure 9.1 Molecular weight distributions for ActiveSight, ChemBridge and Maybridge fragment libraries. Figure 9.1 Molecular weight distributions for ActiveSight, ChemBridge and Maybridge fragment libraries.
See other pages where Maybridge is mentioned: [Pg.386]    [Pg.402]    [Pg.411]    [Pg.460]    [Pg.101]    [Pg.101]    [Pg.101]    [Pg.102]    [Pg.104]    [Pg.104]    [Pg.105]    [Pg.108]    [Pg.108]    [Pg.402]    [Pg.447]    [Pg.68]    [Pg.266]    [Pg.266]    [Pg.119]    [Pg.229]    [Pg.39]    [Pg.212]    [Pg.224]    [Pg.224]    [Pg.225]    [Pg.225]    [Pg.226]    [Pg.226]    [Pg.227]    [Pg.228]    [Pg.228]   
See also in sourсe #XX -- [ Pg.402 , Pg.411 ]

See also in sourсe #XX -- [ Pg.402 , Pg.447 ]

See also in sourсe #XX -- [ Pg.93 , Pg.426 ]

See also in sourсe #XX -- [ Pg.93 , Pg.367 ]



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Fragment libraries Maybridge

Maybridge Library Compound Databases

Maybridge compound library

Maybridge database

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