Maturity onset diabetes of youth

Type 1 DM idiopathic is a nonimmune form of diabetes frequently seen in minorities with intermittent insulin requirements. The prevalence of type 1 DM has been increasing over the last one hundred years. Maturity onset diabetes of youth (MODY), which has an identifiable genetic defect in the glucokinase gene, and endocrine disorders such as acromegaly and Cushing s syndrome, can be secondary causes of DM. These unusual etiologies, however, only account for 1% to 2% of the total cases of type 2 DM. See the section on other forms of diabetes mellitus later in this chapter for further discussion. 

Maturity onset diabetes of youth (MODY) is characterized by impaired insulin secretion with minimal or no insulin resistance. Patients typically exhibit mild hyperglycemia at an early age. The disease is inherited in an autosomal dominant pattern with at least three different... 

MODY maturity onset diabetes of youth NCEP-ATP National Cholesterol Education Program Adult Treatment Panel... 

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