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Mass spectrometry protein extraction studies, FFPE

In a separate study, a protocol for Matrix-assisted laser desorption-ionization (MALDI) imaging mass spectrometry (IMS) has been proposed.18 This IMS technique provides a new approach to visualize spatial distribution of thousands of molecular species, including peptides, proteins, and their metabolites in two- or three-dimensional levels. This approach may also provide a straightforward method of determining the tissue distribution of multiple peptides or proteins in a quantitative manner.18 Chu et al.19 reported a nondestructive molecular extraction method to obtain proteins from a single FFPE or frozen tissue section, without destroying the tissue morphology, such... [Pg.394]


See other pages where Mass spectrometry protein extraction studies, FFPE is mentioned: [Pg.89]    [Pg.96]    [Pg.336]    [Pg.391]    [Pg.392]    [Pg.89]    [Pg.96]    [Pg.391]    [Pg.348]    [Pg.348]    [Pg.392]   


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