Mass analysed ion kinetic energy spectrometry

A) MASS-ANALYSED ION KINETIC ENERGY SPECTROMETRY (MIKES)... 

Mass-analysed ion kinetic energy spectrometry (MIKES) A form of MS-MS product-ion scan that may be carried out on a reversed-geometry double-focusing mass spectrometer. 

MIKES Mass-analysed ion kinetic energy spectrometry... 

MIKES Mass-analysed Ion Kinetic Energy Spectrometry CAR Collision-Activated Reaction... 

A similar technique applicable to reverse geometry mass spectrometers (magnetic sector before electrostatic analyser) is that of mass-analysed ion kinetic energy spectrometry (MIKES). In this technique the ion to be studied is isolated by the magnet and induced to fragment by collision activation in a small chamber filled with a gas such as helium. The product ions are then detected by scanning the electrostatic analyser voltage. 

Bozorgzadeh, M. H., Morgan, R. P. and Beynon, J. H. (1978) Application of mass-analysed ion kinetic energy spectrometry (MIKES) to the determination of the structures of unknown compounds, Analyst 103, 613-622. 

FAB-m.s. conditions have been studied using mass-analysed ion kinetic energy spectrometry the main pathway for methyl glycosides involved loss of methanol. 

Gas-phase acid-base studies are usually performed by using one of the following techniques high-pressure mass spectrometry (HPMS), chemical ionization mass spectroscopy (CIMS) with mass-analysed ion kinetic energy spectroscopy/collision induced dissociation (MIKES/CID), flowing afterglow (FA) or ion cyclotron resonance (ICR) spectrometry. For a brief description of all methods, Reference 8 should be consulted. 

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