Martinet dioxindole reaction

This reaction was initially reported by Martinet in 1913. It is a synthesis of dioxindole derivatives by alkali treatment of the condensation products from substituted anilines and ethyl or methyl ester of oxomalonic acid in the absence of oxygen. Thus it is known as the Martinet reaction. In the presence of oxygen, the dioxindoles are further oxidized into isatins. This reaction has been extended to the preparation of a- and -naphthisatins." ... 

Martinet reactions, though treatment of preformed iV-phenylglyoxamides such as 14 with Cu(II) catalysts have been reported to give either dioxindole 15 or isatin 16 in good yields. ... 

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