Markers ischemia modified albumin

Given the understanding that release of cardiac troponin into the circulation reflects myocardial cell death, it is understandable why, clinically, therapies are oriented toward inhibiting the pathophysiologic processes of thrombosis, fibrinolysis, platelet aggregation, and inflammation leading to ischemia and, ultimately, myocardial cell death. Several markers of ischemia have been proposed [2], and research and development studies are underway to adequately validate their clinical usefulness or lack of evidence. These include the topic of this chapter (ischemia-modified albumin [IMA]), as well as choline, unbound free fatty acids, and nourin. 

Sinha MK, Gaze DC, Tippins JR, Collinson PO, Kaski JC. Ischemia modified albumin is a sensitive marker of myocardial ischemia after percutaneous coronary intervention. Circulation 2003 107 2403-2405. 

Sinha MK, Roy D, Gaze D, Collinson PO, Kaski JC. Role of ischemia modified albumin, a new biochemical marker of myocardial ischemia, in the early diagnosis of acute coronary syndromes. Emerg Med J 2004 21 29-34. 

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