Marker compound dispersion

Chemical contamination of some groundwater and surface-water supplies may have occurred as a result of point-source, waste disposal practices located near State College, PA and the Pennsylvania State University. The compound, unidentified, but having a consistent retention time for elution in the analytical method used for tracing and quantification, will be further described as a marker compound in order to properly focus on the dispersal aspects of this problem. It... 

Microgels synthesised using vinylpyrrolidone co-polymerised with AA have been investigated by Sahoo et al. as an oral drug delivery device [97]. The microgel particles under investigation were loaded with a marker compound, FITC-dextran, and the release of this compound was monitored as function of pH and temperature. The compound release was found to be slow in an acid solution, when the structure is collapsed, but rapidly increased with increasing pH. The release was also found to be temperature dependent. At 4°C arormd 18% of the FITC-dextran was released whereas approximately 50% was released when the dispersion was heated (37°C). 

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