Manipulation of Single Chains Force-Induced Detachment and Translocation Through Pores

5 Manipulation of Single Chains Force-Induced Detachment and Translocation Through Pores 

1 Detachment of Adsorbed Polymer Chain Statics and Dynamics 

With the development of novel single macromolecule experiments, the manipulation of individual polymer chains and biological macromolecules is becoming an important method for understanding their mechanical properties and characterizing 

In Fig. 14a one can see the isotherms of the order parameter, n = N N, against the surface attraction e for different pulling forces,/, which resemble closely those of a conventional first-order phase transition. However, as indicated by the corresponding PDF W(n) (cf. Fig. 14b), the adsorption-desorption first-order phase transition under pulling force has a clear dichotomic namre (i.e., it follows an either/or scenario) in the thermodynamic limit N co there is no phase coexistence The configurations are divided into adsorbed and detached (or stretched) dichotomic classes. The metastable states are completely absent. 

Last but not least, we would like to point out a very recent investigation [64] in which we show that the change of detached monomers with time is governed by a differential equation that is equivalent to the nonlinear porous medium equation. 

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