Manganimetry in Neutral and Weakly Alkaline Media

Recall that the redox couple of manganese playing a part in these conditions is Mn04 -f- 4H+ + 3e Mn02(s) + 2H2O, 

Let s also recall that this couple is a strong oxidant, despite the weakly alkahne medium [atpH = 9, ° (MnO4 /MnO2(s))=0.97 V]. 

Whereas in acidic medium, permanganate ions oxidize iodide ions to give iodine, in neutral and weakly alkaline medium, iodate ions are formed. This is logical since 

In organic analysis, the oxidizing power of permanganate ions in neutral or weakly alkaline medium permits the determination of some alcohols, oxalic and formic acids, and their salts with the production of carbon dioxide. In these pH conditions, permanganate ions react faster than in acidic medium. 

It is not possible to draw general rules indicating the organic structures that undergo quantitative oxidization with potassium permanganate. The stability of the compounds to be determined and the experimental conditions considerably influence the course of the oxidization reaction. We mention some examples here taken from the field of pharmaceutical analysis  

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