Manganese triacetate enones

Salts of other transition metals including vanadium, cerium, chromium and manganese have been used for a-oxygenation, although rarely applied in synthesis. Manganese triacetate has been used for the efficient a -oxidation of enones (Section 2.3.2.2.1.i), but appears not to have been used for the a-hydrox-ylation of saturated ketones des]Hte its known ability to form the corresponding a-keto radicals. Similarly the use of Lewis acid assisted enolization in the oxidative process appears to have been limited to the LTA-mediated examples. 

Manganese triacetate has been specifically reported as a reagent for a -oxidation.Mechanistic dualism analogous to LTA (vide supra) is observed, although the radical process may be more dominant. Watt and coworkers used this technique during the synthesis of quassinoids. Enone (113) was con-... 

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