Manganese catalase crystal structure

Scheme 8. A proposed mechanism for the disproportionation of hydrogen peroxide by manganese catalase, based on the mechanism proposed by Penner-Hahn in 1992, and the T. thermophilus catalase crystal structure. [Adapted with permission from (24). Copyright 1992 WILEY-VCH Verlag.]...

Barynin, V.V., Whittaker, M.M., Antonyuk, S.V., Lamzin, V.S., Harrison, P.M., Artymiuk, PJ. and Whittaker, J.W. (2001) Crystal structure of manganese catalase from Lactobacillus plantarum,... 

Crystal structures of manganese catalases (in the (111)2 oxidation state) from Lactobacillus plantarum,its azide-inhibited complex, " and from Thermus thermophilus have been determined. There are differences between the structures that may reflect distinct biological functions for the two enzymes, the L. plantarum enzyme functions only as a catalase, while the T. thermo-philus enzyme may function as a catalase/peroxidase. The active sites are conserved in the two enzymes and are shown schematically in Figure 32. Each subunit contains an Mu2 active site,... 

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