Mancozeb structure

Mancozeb has effects on various organ systems. Its primary mechanism of toxicity is via skin contact, leading to contact dermatitis and dermal sensitization. Mancozeb has also been shown to have teratogenic and reproductive effects. Mancozeb exposure also alters the reproductive and endocrine structures, leading to decreased fertility. Animals orally exposed to mancozeb showed thyroid hyperplasia, probably via its ability to inhibit the synthesis of thyroxin. Additionally, mancozeb exposure produces neurotoxicity via yet an unknown mechanism. 

Maneb or mancozeb. The analysis of alkylenebis(dithiocarbamates) of some bivalent metal ions is hampered by their low solubility, low stability, and polymeric structure (Bardarov and Zaikov 1989). Furthermore, the methods developed for their determination have low selectivity. Indirect methods include spectrophotometric, gas chromatographic (GC), or thin-layer chromatographic (TLC) determinations of the reaction products, liberated after reduction (in an acidic medium) by carbon disulfide (Bardarov and Zaikov... 

Mancozeb is the manganese-zinc double salt of N,N-ethylene-bisdithiocarbamic acid. This compound is more stable than the derivatives described above (Bontoyan and Looker, 1973) this property has been attributed to the polymeric structure of mancozeb. Mancozeb is not phytotoxic. The polymer generally contains 20% manganese and 2% zinc besides ethylene-bisdithiocarbamate ions. 

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