Mammalian cell-based biosensors

Mammalian cell immobilization to electrode surfaces is vitally important for the construction of cell-based biosensors which hold out the promise for the development of practical methods for the screening of drugs for possible toxic side effects and for the monitoring of the effects of biochemical warfare agents. Surface modification of the substrate could effectively enhance the... 

Various types of biocatalytic materials, such as isolated enzymes, bacterial cells, and intact mammalian and plant tissue sections, are available for the preparation of biocatalytic-based biosensors (3-7), An enzyme, or a group of enzymes, provides the required biocatalytic activity. For the bacterial cell and tissue based systems, the required enzyme is housed in these biocatalytic materials which can help stabilize the enzyme and prolong the biocatalytic activity. 

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