Maltose polysaccharide synthesis

Amino sugars are components of antibiotic substances109 and bacterial polysaccharides,1,0 and are therefore of interest. The nucleoside antibiotics amicetin, bamicetin, and plicacetin contain, as the sugar residue, a monoaminopentadeoxy disaccharide that is closely related to maltose. In view of the reported antibiotic and antitumor properties of these pyrimidine nucleosides,111,112 the synthesis of aminodeoxy derivatives of maltose would be of interest. 

As has been described, the combined use of two phosphorylases is a powerful tool to convert one carbohydrate into another with a different structure. The idea of phosphorylase coupling was first examined by Waldmann et al. (1986), but had been employed for the synthesis of cellobiose from sucrose (Kitaoka et al., 1992), laminaribiose from sucrose (Kitaoka et al., 1993), trehalose from maltose (Yoshida et al., 1995) and kojioligosaccharides from trehalose (Chaen et al., 1999). Discovery of new phosphorylases and their application through phosphorylase coupling should be a promising area in polysaccharide and carbohydrate engineering. 

Enzymatic hydrolysis of polysaccharides (cellulose, starch) or oligosaccharides (maltose, saccharose, lactose) for the synthesis of food products is another class of processes MBR have been applied to. Paolucci-Jeanjean et al [4.56] have recently reported, for example, the production of low molecular weight hydrolysates from the reaction of cassava starch over a-amylase. In this case the UF membrane separates the enzyme and substrate from the reaction products for recycle. Good productivity without noticeable enzyme losses was obtained. Houng et al [4.57] had similar good success with maltose hydrolysis using the same type of MBR,... 

Synthesis of Amylose from Maltose Monod and Torriani -i obtained a cell-free enzyme preparation from a special variant strain of Escherichia coli that converts maltose into a starchlike polysaccharide and glucose. The enzyme shows a high degree... 

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