Maltose hydrogen bonds

Figure 3. Schematic diagram of the hydrogen-bond structure of p-maltose monohydrate (MALTOS11). The anrows indicate infinite chains. Distances and angles are from the neutron diffraction analysis.

A neutron-diffraction study of /3-maltose monohydrate provided a more defined description of the hydrogen bonding present in the molecule.16 With the exception of the intramolecular bond, 0-2 -H------------... 

The Conformational Properties, including Intramolecular Hydrogen Bonding, of Maltose and Related Compounds. E. Alvarado, O. Hindsgaul, R. U. Lemieux, K. Bock, and H. Pedersen, Abstr. XHth Int. Carbohydr. Symp., July 1-7 (1984) Utrecht, The Netherlands, p. 480. 

Fig. 2.6 a, b. Hydrogen-bond connectivity diagram for maltose monohydrate, a Projection of a section of the crystal structure b schematic connectivity diagram... 

Hydrogen bonding in maltose, maltose monohydrate, and methyl maltoside provide models for that in the amyloses. Again the disaccharides are used as... 

Intramolecular hydrogen bonding stabilizes the macrocycle. As in a-maltose and in -maltose monohydrate, the separation of the 0(2)H and 0(3)H groups on adjacent glucose residues in the cyclodextrin molecules is such that intramolecular interglucose hydrogen bonds can be formed. 

The cooperative, infinite chains and cycles formed by O-H 0 hydrogen bonds in the a-cyclodextrin hydrates are a characteristic structural motif [109]. As with the simpler carbohydrate crystal structures described in Part II, Chapter 13, the hydrogen bonds can be traced from donor to acceptor in the cyclodextrin hydrate crystal structures. Networks of O-H 0-H 0-H interactions are observed in which the distribution of hydrogen bonds follows patterns with two characteristic motifs. One are the "infinite chains which run through the whole crystal lattice, and the others are the loops or cyclically closed patterns (a special case of the "infinite chains). As in the small molecule hydrates, such as a-maltose monohydrate, the chains and cycles are interconnected at the water molecules to form the complex three-dimensional networks illustrated schematically in Fig. 18.5, with some sections shown in more detail in Fig. 18.7 a, b, c. 

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