Malonic acid amides

The heterocoupling of carboxylic acids bearing chiral auxiliaries has been used to study the diastereoselectivity of the coupling of Kolbe radicals [204b]. For that purpose, 2-substituted malonic acid amides bound to seven different chiral auxiliaries were coelectrolyzed with different coacids [Eq. (200]- The yields in heterodimer ranged between 13 to 69%, and the diastereoselectivities between 20 and 86% de. [Pg.939]

Three other methods of forming the 3,5-pyrazolidinedione ring system have been reported. One of these involves oxidation of malonic acid amides with potassium hypochlorite952 or with sulfur and aluminum chloride (eq. 254).1324 The second method is cyclization of... [Pg.143]

A malonic acid derivative of Wang resin has been prepared by reaction with Meldrum s acid and the product converted to a malonamide via the acid chloride. Condensation with an aldehyde under Knoevenagel conditions gave methylene malonic acid-amides that were cleaved from the resin with TFA-H2O [193] (Scheme 7). [Pg.229]

Vecchio and his co-workers (8 2,63,64 synthesize a great variety of isoxazole derivatives. The substrates used were cyanoketones acetoacetates (46,47) jS-oxo-esters (, 64 malonic acid amides ( ). [Pg.168]

Malonic acid amides from malonic acid esters G(GOOR)2 G(GONH2)2... [Pg.519]

Malonic acid amides from maionic acid esters... [Pg.101]

Sodium hydroxidelliq. ammonia Barbituric acids from malonic acid amides... [Pg.492]

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