Malaria ferroquine

Sanofi (2011) Dose Ranging Study of Ferroquine with Artesunate in African Adults and Children with Uncomplicated Plasmodium Falciparum Malaria. ClinicalTrials.gov http //clinicaltrials.gov/ ct2/show/NCT00988507 (accessed Nov. 13, 2011). 

The other current example involves malaria. Chloroquine, 19, one of the currently prescribed antimalarials, is subject to resistance phenomena, while ferroquine 20, surprisingly, does not have this problem. The latter product is currently in clinical development at Sanofi-Aventis [73]. All of these recent developments are discussed in detail, with further examples, in Chapter 3. 

Ferroquine, a New Weapon in the Fight T inst Malaria the Archetypical Bioorganometallic Approach... 

Recently, chloroquine has been successfully modified with a ferrocenyl entity incorporated widiin the side chain of the drug. This drug named ferroquine is active against chloroquine-resistant strains of die malaria parasite (38). This molecule is an example of the development of bioorganometallic chemistry in die design of drugs. 

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