Malabsorption syndromes tropical sprue

Malabsorption syndrome Steatorrhea Tropical sprue Idiopathic hypercalcemia... 

Glucocorticoid antagonism Idiopathic hypercalcemia Malabsorption syndrome Sarcoidosis Steatorrhea Tropical sprue... 

Normally there is very little fat in the feces. However, fat content in stools may increase because of various fat malabsorption syndromes. Such increased fat excretion is steatorrhea. Decreased fat absorption may be the result of failure to emulsify food contents because of a deficiency in bile salts, as in liver disease or bile duct obstruction (stone or tumor). Pancreatic insufficiency may result in an inadequate pancreatic lipase supply. Finally, absorption itself may be faulty because of damage to intestinal mucosal cells through allergy or infection. An example of allergy-based malabsorption is celiac disease, which is usually associated with gluten intolerance. Gluten is a wheat protein. An example of intestinal infection is tropical sprue, which is often curable with tetracycline. Various vitamin deficiencies may accompany fat malabsorption syndromes. 

Malabsorption syndromes. Particularly in gluten-sensitive enteropathy and tropical sprue, poor absorption of folic acid from the small intestine often leads to a megaloblastic anaemia. 

Malabsorption Syndromes. Patients at risk include those with celiac disease, tropical sprue, cystic fibrosis, and short bowel syndrome. Excessive intake of oral zinc supplements can cause anemia and hematological abnormalities in the absence of occult blood loss. The copper deficiency is caused by zinc induction of metallothionein in the mtesti-nal mucosa, which then sequesters dietary copper, blocking its absorption. 

Malabsorption syndromes (e.g., tropical sprue, celiac disease, radiation enteritis or intestinal lymphectasia)... 

Tropical sprue is a malabsorption syndrome of unknown etiology affecting the absorption of a wide range of nutrients. Evidence suggests that the primary mucosal lesion may be due to an infectious agent but this has not been confirmed. However, the response to antibiotics (Til, K5) and its epidemiology provides some support for this suggestion. The syndrome is... 

Neomycin causes a malabsorption syndrome, similar to that seen with non-tropical sprue. The effect is to impair the absorption of a number of drugs including digoxin , (p.906) and methotrexate , (p.642). 

Tropical sprue. An intestinal malabsorption syndrome of infectious origin commonly found in the tropical regions. This syndrome is characterized by acute or chronic diarrhoea and consequently weight loss and malabsorption of nutrients. 

In the course of malabsorption syndromes an increased excretion of 5-hydroxyindole acetic acid and of 3-indoleacetic acid " was observed. In the case of non-tropical sprue there was an increase of serotonin in the blood (1436) excretion of 5-hydroxyindole acetic acid. " " ... 

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