Macromolecular crystallization automated

Bard, J., Ercolani, K., Svenson, K., Olland, A., and Somers, W. 2004. Automated systems for protein crystallization. In Methods A Companion to Methods in Enzymology Macromolecular Crystallization (ed. A. McPherson) 34(3) 329-347. 

In the case of x-ray diffraction, important advances include the use of robotics to ensure successful growth of crystals, the development of synchrotron sources for macromolecular crystallography, the use of direct methods and anomalous dispersion in phasing, and the development of automated methods of map htting. 

Automation will be a major key for the success of stmctural genomics. The development of effective macromolecular stmcture detemiination facilities using intense X-rays from synchroton sources and advances in protein expression, purification and crystallization are accelerating the process of determining the structures of target niacroniol-ecules.t" " ... 

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