M-Allylpyrocatechin methylene ether

Safrole. 5-(2-Propenyl)-I,3-frenzodioxofe 4-allyl-1,2-melhylenedioxybtnzene allylcatechol methylene ether allyldioxybenzene methylene ether m-allylpyrocatechin methylene ether. C H O, mol wt 162.18. C 74.05%, H 6.22%, O 19.73%. Constituent of several essential oils, notably of sassafras in which it is present to the extent of about 75%. Has been used as topical antiseptic pediculicide. Metabolism studies Oswald et al.. Biochim Biophys. Acta 230, 237 (1971). Review and evaluation of studies of carcinogenic action in laboratory animals. IARC Monographs 10, 231-241 (1976). Toxicity data Hagan el al, Toxicol Appl Pharmacol. 7, 18 (1965). 

METHYLENE ETHER l-ALLYL-3,4-METHYLENEDIOXYBENZENE 4-ALLYL-1,2-METHYLENEDI0XYBENZENE m-ALLYLPYROCATECHIN METHYLENE ETHER 4-ALLYLPYROCATECHOL FORMALDEHYDE ACETAL ALLYLPYROCATECHOL METHYLENE ETHER l,2-METHYLENEDIOXY-4-ALLYLBENZENE 3,4-METHYLENEDIOXY-ALLYBENZENE 5-(2-PROPENYL)-l,3-BENZODIOXOLE RHYUNO OIL SAFROLE SAFROLE ME SHIKIMOLE SHDCOMOL... 

CAS 94-59-7 EINECS/ELINCS 202-345-4 Synonyms 5-Allyl-1,3-benzodioxole Allylcatechol methylene ether Allyidioxybenzene methylene ether 1-Allyl-3,4-methylenedioxybenzene 4-Allyl-1,2-methylenedioxybenzene m-Allylpyrocatechin methylene ether Allylpyrocatechol methylene ether 1,2-Methylenedioxy-4-allylbenzene 3,4-Methylenedioxy allylbenzene 3,4-Methylenedioxy-1-allylbenzene 5-(2-Propenyl)-1,3-benzodioxole Safrole Empiricai C10H10O2 Formuia C3H5C6H3O2CH2 Properties Colorless vise. liq. orcryst. sassafras odor very sol. in alcohol misc. with chloroform, ether, chlorinated solvs. insol. in water m.w. 162.20 dens. 1.0960 (20 C) m.p. 11 C b.p. 234.5 C flash pt. 100 C ref. index 1.5360-1.5385 Toxicoiogy LD50 (oral, rat) 1950 mg/kg,... 

---