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Lymphocyte-predominant thymoma

LYMPHOCYTE-PREDOMINANT THYMOMA VERSUS LYMPHOID HYPERPLASIA... [Pg.343]

The most helpful immunostain in this differential diagnosis—and one that the author, through regrettable mistakes, has made routine—is an assessment of keratin reactivity. The elaborately interconnecting epithelial cells of lymphocyte-predominant thymoma (LPT), which are not seen in LL, are distinctive. This pattern is essential to differential diagnosis, because LL and other lymphomas of thymus may demonstrate entrapped non-neoplastic thymic epithelial cells that are visible (but widely separated and non-interconnecting) on keratin immunostains. 3 Another potential marker for thymic epithelium—p63 protein" —is not as useful in this particular contextual setting. That is true because LL may be p63-reactive as well." ... [Pg.343]

FIGURE 11.1 Keratin in lymphocyte-predominant thymoma (A). Note the delicately interlocking pattern of reactivity (B). [Pg.344]

The favored nosologic scheme for thymomas groups them into several discrete categories based on microscopic morphology lymphocyte predominant (>66%... [Pg.341]

See other pages where Lymphocyte-predominant thymoma is mentioned: [Pg.343]    [Pg.343]    [Pg.343]   


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