Luteolin absorption

Shimoi, K., Okada, H., Furugori, M., Goda, T., Takase, S., Suzuki, M., Hara, Y., Yamamoto, H., and Kinae, N., Intestinal absorption of luteolin and luteolin 7-0- 3-glucoside in rats and humans, FEBS Lett., 438, 220, 1998. 

Data on the absorption of flavones (namely luteolin) are limited. Shimoi... 

Neohydnocarpin (80), C24H20O9, showed a UV absorption spectrum typical of a flavone. Detailed NMR spectroscopic analysis led to the proposal of the presence of a luteolin (118) and a coniferyl alcohol moiety (45). Careful examination of the C NMR spectrum showed the absence of oxygen functions at C-7" and C-8", which resonated at 35.2 and 40.9 ppm, compared to those in silybin A (89) at Sc... 

Lucenin-1 has the same ultraviolet absorption spectrum as that of luteolin and orientin, and shows the same diagnostic shifts it gives no sugar under conditions normal for the acid hydrolysis of glycosides, and... 

We investigated the in vitro absorption and metabolism of nobiletin and compared these with luteolin. Nobiletin preferentially accumulated in a differentiated Caco2 cell monolayer, used as a model for small intestinal epithelial cells in contrast, luteolin did not [61], Treatment of nobiletin with rat liver S-9 mixture led to the formation of 3 -demethylnobiletin, whereas luteolin was unaffected. We concluded, therefore, that PMFs including nobiletin have properties separate and distinct from those of common flavonoids for absorption and metabolism in vitro [61],... 

Shimoi K, Okada H, Furugori M, Goda T, Takase S, Suzuki M, Hara Y, Yamamoto H, Kinae N. Intestinal absorption of luteohn and luteolin 7-O-beta-glucoside in rats and humans. FEBS Letters 1998 438 220- 224. 

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