Lupus vulgaris

Since the initial report of lupus vulgaris following BCG immunization in 1946, about 60 cases have been published, mostly following (multiple) revaccination. 

The risk of developing lupus vulgaris following primary immunization is extremely low. 

Lupus vulgaris occurred in a 7-year-old girl after only a single BCG immunization (47). She was treated with conventional antituberculosis therapy with an excellent response. 

Six months after BCG vaccination, an 18-year-old man developed lupus vulgaris on his right shoulder (48). He was successfully treated with rifampicin, isoniazid, and ethambutol. He had had lupus vulgaris after BCG vaccination on his left shoulder 8 years before. 

Kanwar AJ, Kaur S, Bansal R, Radotra BD, Sharma R. Lupus vulgaris following BCG vaccination. Int J Dermatol 1988 27(7) 525-6. 

Sasmaz R, Altinyazar HC, Tatlican S, Eskioglu F, Yurtsever P. Recurrent lupus vulgaris following repeated BCG (Bacillus Calmette Guerin) vaccination. J Dermatol 2001 28(12) 762-4. 

Hellerstrom S (1951) Collected cases of inoculation lupus vulgaris. Acta Derm Venereol 31 194-211... 

Dowling, G. B., Prosser Thomas, E. W. 1946. Treatment of lupus vulgaris with calciferol. Lancet 1 919-22. 

Farsinejad K, Daneshpazhooh M, Sairafi H, Barzegar M, Mortazavizadeh M. Lupus vulgaris at the site of BCG vaccination report of three cases. Clin Exp Dermatol 2009 34 el67-9. 

Patiala, R. (1949). Application of usnic acid to a case of lupus vulgaris. Ann. Med. Exp. Biol. Fenn. 27, 151. 

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