Lung, bioluminescence imaging

Bioluminescence Imaging of Transcription Factor Activity in the Lungs ... 

Figure 10.3 (See color insert) Bioluminescent imaging of a wild-type mouse after implantation of a light emitting bead (with a spectrum similar to that of firefly luciferase) in the pleural space posterior to the right lung (a), in the pleural space anterior to the right lung (h), or anterior to the rih cage (c). The pseudocolor scale is shown and the region of interest (ROI) for photon detection is indicated by a red circle. Detected photon counts are indicated for each ROI.

Figure 10.7 (See color insert) (a) Representative bioluminescent images from HLL mice prior to treatment (baseline) and 72 h after intratracheal treatment with adenoviral vectors expressing I/rB-aDN, cIKKl, or cIKKl + I/cB-aDN. Photon emission from the area of the thorax overlying the lungs is identified by arrows and quantified (b). Mean +/— SEM, P < 0.05 compared with other groups. Reprinted with permission from Ref. (55).

Imaging Cellular and Molecular Processes in the Lung Using Bioluminescent Reporter Genes... 

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