Lowary and Callam

Aiming at the discovery of novel inhibitors of cell wall arabinan portion biosynthesis, Lowary and Callam [10] designed an elegant route to methyl carbafuranosides 43 and 44, employing, as the key step, a ring closing metathesis reaction. 

Callam, C. S. Singer, S. J. Lowary, T. L. Hadad, C. M. Computational analysis of the potential energy surfaces of glycerol in the gas and aqueous phases Effects of level of theory, basis set, and solvation on strongly intramolecularly hydrogen-bonded systems, J. Am. Chem. Soc. 2001,123,11743-11754. 

Callam, C S, Lowary, T L, Synthesis and conformational investigation of methyl 4a-carba-D-arabinofuranosides, J. Org. Chem., 66, 8961-8972, 2001. 

C. S. Callam and T. L. Lowary, Total synthesis of both methyl 4a-carba-D- arabinofuranosides, Org. Lett., 2 (2000) 167-169. 

Gadikota, R.R., Keller, A.I., Callam, C.S., and Lowary, T.L. (2003) Efficient synthesis of trans-(-L)-laurediol from carbohydrate precursors. Tetrahedron Asymmetry, 14, 737-742. 

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