Losartan Phenobarbital

In a placebo-controlled study 15 healthy subjects were given phenobarbital 100 mg daily for 16 days with a single 100-mg dose of losartan. Phenobarbital slightly reduced the AUC of losartan and its active metabolite,... 

P-gp (ABCB1) Verapamil, digoxin, mitoxantrone, vinblastine, doxorubicin, losartan, talinolol, cortisol, dexamethasone, colchicine, loperamide, domperidone, indinavir, erythromycin, tetracycline, itraconazole, cyclosporine, methotrexate, amitryptyline, phenobarbital, morphine, cimetidine, and others... 

Drugs that may interact with losartan include cimetidine, phenobarbital, fluconazole, indomethacin, and rifamycins. 

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