Long-acting thyroid stimulators

Furth ED, Rathbun M, Postillico J. A modified bioassay for the long-acting thyroid stimulator (LATS). Endocrinology 1969 85 592-3. 

EATS Long-acting thyroid stimulator PDGF Platelet-derived growth factor... 

D2a. Dobyns, B. M., Rudd, A., and Liebe, D., The assay of the exopthalmus-produoing substance (EPS) and the long-acting thyroid stimulator (LATS) in whole and fractionated serum of patients with progressive exopthalmos. In Current Topics in Thyroid Research (C. Cassano and M. Andreoli, eds.), pp. 484-499. Academic Press, New York, 1965. 

D3. Dorrington, K. J., and Munro, D. S., The long-acting thyroid stimulator. Clin. Pharmacol. Therap. 7, 788-806 (1966). 

F2. Field, J. B., Remer, A., Bloom, G., and Kriss, J. P., In vitro stimulation of long-acting thyroid stimulator of thyroid glucose oxidation and P incorporation into phospholipid. J. Clin. Invest. 47, 1553-1560 (1968). 

K6. Kriss, J. P., Pleshakov, V., and Chien, J. R., Isolation and identification of the long-acting thyroid stimulator and its relation to hyperthyroidism and circumscribed pre-tibial myxedema. J. Clin. Endocrinol. Metab. 24, 1005-1028 (1964). 

L3. Lepp, A., and Oliner, L., Failure of long-acting thyroid stimulator globulin (LATS) and serum to stimulate thyroid function in the chick. Endocrinology 80, 369-374... 

McKenzie, J. M., Fractionation of plasma containing the long acting thyroid stimulator. J. Biol. Chem. 287, 3571-3572 (1962). 

McKenzie, J. M., The long-acting thyroid stimulator Its role in Graves disease. Recent Progr. Hormone Res. 23, 1-46 (1967). 

McKenzie, J. M., and Williamson, A., Experience with the bioassay of the long-acting thyroid stimulator. J. Clin. Endocrinol. Metab. 26, 518-526 (1966). McKenzie, J. M., Adiga, P. R., and Murthy, P. V. N., Effects of actinomycin-D, cycloheximide and puromycin on thyroid stimulation. Endocrinology 83, 1132-1139 (1968). 

Meek, J. C., Jones, A. E., Lewis, V. J., and Vanderlaan, W. P., Characterization of the long-acting thyroid stimulator of Graves disease. Proc. Natl. Acad. S[Pg.420]

Sunshine, P., Kusumoto, H., and Kriss, J. P., Survival time of circulating long-acting thyroid stimulator in neonatal thyrotoxicosis Implications for diagnosis and therapy of this disorder. Pediatrics 36, 869-876 (1965). 

Long-acting thyroid stimulator (LATS). Former term for TSH-R stimulating autoantibodies. See also thyroid-stimulating... 

Long-acting thyroid stimulator (LOTS) original name for the autoantibodies of Graves disease... 

Long-acting thyroid stimulator Luteinizing hormone assay... 

It is probable that the more recently discovered immunoglobulins, all in the IgG class, such as long-acting thyroid stimulator (LATS) and LATS protector, should be classified as thyroid autoantibodies and discussion on these follows in the next section. 

B8. Bitensky, L., Alaghband-Zadeh, J., and Chayen, J., Studies on the thyroid stimulating hormone and the long-acting thyroid stimulating hormone. Clin. Endocrinol. 3,363-374 (1974). 

By determining the radioactivity in blood samples 9-24 h after the material to be assayed has been injected, it is also possible to assay the long-acting thyroid-stimulating immunoglobulin (LATS). 

In addition to these three autoantibodies, there is a protein known as long-acting thyroid stimulator (LATS). This can also be considered as a thyroid autoantibody since it is an immunoglobulin which causes overstimulation of the thyroid... 

---