Lobophytum hedleyi

Lobohedleolide (555) and (7Z)-lobohedleoUde (556) were two new cembranolides from Lobophytum hedleyi. Lobohedleolide (555) produced in vitro growth inhibition of Hella cells at 5 pg/mL (433). 

UcHio, Y., J. Toyota, H. Nozaki, M. Nakayama, Y. Nishizono, and T. Hase Lobohedleolide and (7Z)-Lobohedleolide, New Cembranolides from the Soft Coral Lobophytum hedleyi Whitelegge. Tetrahedron Lett. 22, 4089 (1981). 

Bowden, B.F., Coll, J.C., Liyanage, N Mitchell, S.J., Stokie, G.J., and Van Altena, I.A. (1978b) Studies of Australian soft corals. IV. A novel bicyclic diterpene from Lobophytum hedleyi. Aust. J. Chem., 31, 163-170. 

Uchio, Y, Toyota, J., Nozaki, H., Nakayama, M., Nishizono, Y, and Hase, T. (1981) Lobohedleolide and (7Z)-lobohedleolide, new cembranolides from soft coral Lobophytum hedleyi Whitelegge. Tetrahedron Lett., 22, 4089-4092. 

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