Lithium butyl cuprate

According to this disconnection the butyl group is derived from lithium dibutyl cuprate A suitable preparation is... 

Lithium, methyl, 55,7, 10 Lithium, phenyl-, 55,11 Lithium phenylthio(alkyl)cuprates, 55,122 LITHIUM, phenyltluo(fe/f-butyl)cuprate [Lithium, phenylthio( 1,1 -dimethyl-ethyl)cupiate, 55,122 Lithium, 1-propenyl-, 55, 111 LITHIUM, ( >l-propenyl-, 55, 103 Lithium thiophenoxide [Ben7enethiol, lithium salt], 55, 122... 

Lithium bis(l-methylpropyl)cuprate [Lithium bis(2-butyl)cuprate], 55, 112 Lithium bromide, 55, 129 Lithium, butyl-, 55, 1, 10, 39, 122 Lithium, 1,1 dimethylethyl- [Lithium, tert-butyl ], 55, 123... 

Prim, und sek. Sulfonsaure-ester lassen sich selektiv auch mit den Systemen 2 Lithium-trimethoxy-hydrido-aIuminat/Kupfer(I)-jodid6 und Lithium-butyl-hydrido-cuprat(I)7 zu... 

Substitution of alfylic sulfoxides. Lithium dimethyl cuprate and di-n-butyl cuprate react with allylic sulfoxides or sulfones mainly by y-substitution to give tri-substituted alkenes (equation I).15... 

A report of House, Respess and Whitesides (47) showed that the reaction of lithium dimethyl cuprate with the unsaturated ketone 135 gave exclusively the ketone J36 having the methyl trans to the t-butyl group. In this case where the double-bond is exocyclic, stereoelectronic effects allow equal attack from either face. Thus, the exclusive formation of 136 must be due to steric reasons only, the equatorial approach being favored. 

Iithio-3-ethoxypyridine, obtained by the reaction of 3-ethoxypyridine with n-butyl-lithium and TMEDA in THE at — 40 °C, reacts with a wide range of electrophiles to give 2,3-disubstituted pyridines. Esters (R COOR ) are obtained by the reaction of 5-2-pyridylthioates (2-CsH4N-S-COR ) with lithium dialkyl-cuprates (R jCuLi) under oxygen. The reaction of these substrates in a nitrogen atmosphere is known to produce ketones (R COR ). 

Table 8.20. Relative Reactivity of Lithium Di-ra-butyl Cuprate with Alkyl Halides...

CONJUGATE ADDITION Alkylmethyl-magncsiocuprates. 2-Carboethoxyl-benzyl phenyl sulfoxide. Cyanodiethyl-aluminum chloride. 1-Cyclopropyl-l-tiimethylsilyloxyethylene. Lithium 1,3-butadiene-l-olate. Lithium dimethyl-cuprate. Magnesium ethyl malonate. Potassium carbonate. Tri-n-butyl-stannyllithium. Trimethylzinclithium. 

Lithium bis(2-butyl)cuprate [Lithium bis-(l-methylpropyl)cupiate, 55, 112 Lithium dialkylcuprates, 55, 112 Lithium diraethylcuprate, 55,112 Lithium diphenylcuprate, 55, 112 LITHIUM DIPROPENYLCUPRATE, 55, 103, 111... 

---