Liquid immersion development advantages

Solid-phase microextraction (SPME) was developed in 1988 by Prof. Janusz Pawliszyn and his coworkers at Waterloo University in Ontario, Canada, and commercialized in 1993 by Supelco (28-32). Solid-phase microextraction is an innovative, completely solvent-free sample preparation method that can be used to concentrate flavors and fragrances and that significantly reduces the time and cost required for sample preparation it therefore represents an excellent alternative to conventional sample extraction techniques. The advantages of SPME are particularly remarkable because this solvent-free sample preparation method does not require any complex or expensive equipment. This highly effective technique can be used to concentrate volatile organic compounds from liquid samples (immersion SPME) or from the headspace above a liquid or solid sample (headspace SPME). 

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