Liquid drug formulations

Theeuwes, F. and Yum, S.I. (1976). Principles of the design and operation of generic osmotic pumps for the delivery of semisolid or liquid drug formulations. Ann. Biomed. Eng. 4 343-353. 

Figure 12.19 Drug delivery curves obtained with an implantable osmotic pump [30], Reprinted from F. Theeuwes and S.I. Yum, Principles of the Design and Operation of Generic Osmotic Pumps for the Delivery of Semisolid or Liquid Drug Formulations, Ann. Biomed. Eng. 4, 343, 1976, with permission of Biomedical Engineering Society...

A hydrodynamic pressure-activated drug-delivery system can be fabricated by placing a liquid drug formulation inside a collapsible, impermeable container to form a drug reservoir compartment. This is then contained inside a rigid, shape-retaining housing. A laminate of an absorbent layer and a swellable,... 

Inhalers. Various aerosols can deliver liquid drug formulations. The hquid units are inserted into the device which generates the aerosol and delivers it directly to the patient. This avoids any problems associated with converting proteins into powders. This method has applications in delivery of morphine and insulin. 

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